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KMID : 0359920080270030364
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Korean Journal of Nephrology
2008 Volume.27 No. 3 p.364 ~ p.368
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A Case of Idiopathic Fibrillary Glomerulonephritis with Hypocomplementemia
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Yoon Se-Hee
Kang Gu-Hyum
Yun Sung-Ro
Choi Nak-Won
Kim Yoon-Mee
Lim Bum-Jin
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Abstract
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A 72-year-old woman presented with generalized edema and proteinuria. Renal biopsy disclosed highly organized fibrillary deposits in subendothelial area by electron microscopy. The microfibrils were 14 nm in diameter and randomly arranged. They did not have a microtubular appearance. These materials were negative for Congo red staining. Cryoglobulinemia or paraproteinemia including light chains was not found. So we can diagnose her as fibrillary glomerulonephritis (GN). In fibrillary GN serum complement levels are usually normal except in rare cases with systemic disease. Here we present a rare case of fibrillary GN with unusual hypocomplementemia.
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KEYWORD
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Microfibrils, Glomerulonephritis, Complement 3
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